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Household Supplies

Enzyme Cleaners

Best Enzyme Cleaners

Name: Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon
Brand: Rocco & Roxie Supply Co.
Price: 59.97 USD
Availability: InStock

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Rocco & Roxie Supply Co.

Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

9.6

score

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Bioda

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

9.4

score

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Nature's Miracle

Nature’s Miracle Advanced Stain And Odor Eliminator for Dogs, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes, 1 Gallon

9.1

score

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Nature's Miracle

Nature’s Miracle Urine Destroyer Plus Cat, 32 Ounces, Enzymatic Formula, Ready-to-Use

8.8

score

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AmazonCommercial

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

8.5

score

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ANGRY ORANGE

14%OFF

Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 1 Gallon

8.2

score

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Nature's Miracle

Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use

7.9

score

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ANGRY ORANGE

ANGRY ORANGE 1 Gallon Enzyme Cleaner and Deodorizer, Pet Stain and Odor Remover for Dog & Cat Urine and Stains - Citrus, Made in USA

ANGRY ORANGE

13%OFF

ANGRY ORANGE Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 24 oz - Value 2 Pack

7.3

score

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Buying Guide for the Best Enzyme Cleaners

Choosing the best enzyme cleaner means finding one suited to the messes you tackle most often. These cleaners use natural enzymes to break down stains and odors—especially useful for organic messes like pet accidents, food spills, or laundry issues. Think about where and how you’ll use the product: for carpets, upholstery, laundry, or hard surfaces. The key is to blend effectiveness, safety, and ease-of-use so the cleaner can make life easier without compromise. Understanding some core specifications and choosing based on your needs will help you get the most value and satisfaction.

Type of EnzymesEnzyme cleaners contain different kinds of enzymes that target specific types of messes. Common types include proteases (for protein-based stains like blood and food), amylases (for starches like pasta, rice, or sauces), and lipases (for grease and oil). Some products blend all three for broad usage. If pet stains are your main problem, prioritize protease-based formulas. For greasy kitchens, lipase-heavy cleaners work best. Matching the enzyme type to your common messes ensures better cleaning results.

Application SurfaceMany enzyme cleaners are formulated for certain surfaces, such as carpets, upholstery, hard floors, or laundry. Some are multi-surface, while others are specialized. For best results, choose an enzyme cleaner that mentions compatibility with the surfaces you clean most. Using the right formulation helps avoid damage and increases stain-removal effectiveness, so always check the label for supported surfaces before purchasing.

Odor Elimination AbilityEnzyme cleaners usually do double duty, cleaning stains and neutralizing odors. Some are formulated specifically for powerful odor removal—for example, pet urine. To judge the effectiveness, look for claims of deep odor removal, not just masking. If strong smells are your biggest concern, prioritize products with robust odor-neutralizing abilities described on the packaging or in reviews.

Safety and IngredientsA crucial spec is the safety of the formula—especially if you have kids or pets. Many enzyme cleaners are non-toxic, biodegradable, and free of harsh chemicals, which makes them preferable in family environments. Navigate the product descriptions for phrases like 'safe for children/pets,' 'eco-friendly,' or 'biodegradable.' Opt for those if you value safety and environmental friendliness for your household.

Concentration and DilutionEnzyme cleaners often come either ready-to-use or concentrated. Concentrated formulas need to be diluted with water and can be more economical over time, while ready-to-use versions offer convenience. Decide based on your cleaning frequency—if you clean often or large areas, concentrated products give flexibility and can last longer; for quick spot treatments, ready-to-use is simpler.

ScentScent is worth considering if you're sensitive to fragrances or want a pleasant freshness after cleaning. Some enzyme cleaners have a mild, natural scent, others are fragrance-free, and some offer stronger, perfumed options. For those with allergies or preferences for a neutral environment, opt for unscented or lightly scented versions. Choose based on your tolerance and lifestyle for best comfort during and after cleaning.

Best Enzyme Cleaners

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Buying Guide for the Best Enzyme Cleaners